Posts tagged "lymphoma in cats"

Lymphoma – Symptoms And Prevention

Diseases like tumors, sarcoma, melanoma, and lymphoma have threatened many human lives. When we look on any type of cancers we will find many experts are doing research to find out the best cures for the patients. Besides this there are experts in prostate and in acoustic neuroma that have been successful in introducing some form of treatment but still there is much more progress required to treat the large number of patients. Let us move to the disease of Lymphoma, which has become one of the common causes of fatalities these days. Hopefully those suffering from this condition will get some basic help.

What is Lymphoma?

Lymphoma is a type of building up disease which disturbs the cycle of lymphatic system. Lymphatic system is a part of immune system, a system which helps our body to fight against bacteria and viruses. When the system gets disturbed, the disease starts to spread because there is no other way to fight back the bacteria and constant virus attacks inside the body. It is a kind of disease which when spreads in any part of the body starts to decay that section. It is really a cursing disease and has put many lives to suffer.

Often we come to hear about the “Lymph Nodes”. This is the section where lymphoma tends to attack. These nodes are swollen at the time we are carrying any bacterial infection. A time comes when the cells in this section start to develop and their rapid growth curse the section. The final stage of this development results in Lymphoma.

Causes & Symptoms:

With the research, the experts have not declared any definite causes for the diseases as every patient is having his or her own symptom for the disease. However, there are some general risk factors which can give you a bit sign but still there is a deep required to testify the suspected patient.

Age:

There are two age groups who are found with the disease. The first percentile is reported in old people, who are above the age of 60. In children it is recorded in the kids who have a weak or pre-mature immune system.

Already disturbed or weak immune system:

The person with a weaker immune system can easily come under the influence of Lymphoma. A weak immune system itself invites this disease after that it spreads rapidly.

Inherited:

Lymphoma can be inherited. If anyone had the same syndrome in his or her family, then it increases the likelihood for the disease to come back to the person.

Other diseases of stimulation:

There are some diseases which also invites the urgency of Lymphoma. The most common are HIV Aids and hepatitis C.

Prevention:

As the disease does not have any confirmed symptoms, the choices of prevention are also very limited. According to the experts’ advice, you can prevent yourself by eradicating the risk factors. There are some automatic risk factors which you cannot avoid, like inheritance factor. But you can avoid some risk factors which are in your hand like avoid smoking etc.

Stewart Wrighter has been searching the term prostate cancer New York in order to find the latest treatments because he is authoring an article on the subject for a major news magazine. He searched the term acoustic neuroma New York in order to find a specialist in the area.

Living with Lymphoma: A Patient’s Guide
by: Elizabeth M. Adler
publisher: The Johns Hopkins University Press, published: 2005-09-30
ASIN: 0801881803
EAN: 9780801881800
sales rank: 346545
price: $9.25 (new), $0.85 (used)

When neurobiologist Elizabeth M. Adler was diagnosed with non-Hodgkin lymphoma, she learned everything she could about the disease, both to cope with the emotional stress of being diagnosed and to make sure she made the best possible decisions for her treatment. In Living with Lymphoma, she combines her knowledge of lymphoma—both scientific and personal—with the desire to help other patients come to grips with this complex, and often baffling, disease.

Adler thoroughly explains the disease, describing the many different kinds of Hodgkin and non-Hodgkin lymphoma, the wide range of symptoms, and the various treatment options available. Convinced that understanding lymphoma’s biological basis will help patients make better treatment decisions, Adler explains basic cell biology and how the immune system functions. Readers will gain sufficient background to understand and evaluate medical literature, and to ask their physicians questions specific to their own needs.

In the introduction, Dr. Michael R. Bishop of the National Institutes of Health provides a physician’s perspective on the delicate nature of doctor-patient relationships in the context of a life-threatening disease—especially the importance of patient education and open communication in making decisions about treatment options and quality of life.

Drawing on her scientific expertise and personal journey—as well as her empathy, passion, and humor—Adler has created a valuable guide for people with lymphoma and the people caring for them.

Alternative Cancer Treatment Guide

How To Successfully Treat Cancer Using Inexpensive, Proven, Natural Therapies.

Recommended Reading

Be the first to comment - What do you think?
Posted by admin - 05/01/2012 at 5:21 pm

Categories: Lymphatic Cancer, Lymphatic Cancer Symptoms   Tags: , , , , , , , , , , , , , , , ,

Computed Tomography (CT) : Imaging Test For Lymphoma

Imaging test are utilized to discover and look on tumors within the system. All these tests are usually a key a part of jobsite set ups this cancer malignancy — that may be, finding out whenever and just how much it’s got propagate.

Upper body x-ray: Hodgkin disease often creates bloating associated with lymph nodes inside upper body which usually can often be found on the simply upper body x-ray.

Computed tomography (CT) check out: The following test provides a family doctor a better check out lymph nodes inside upper body, belly (belly), and pelvis, and some other internal organs. This Computed tomography (CT) check out is like a x-ray but rather than taking you graphic like a x-ray, a Computed tomography (CT) protection uses a lot of pictures the way it rotates across the individual. A laptop combines all these pictures towards a impression on the “slice” on the system.

Often following your initial pair of pictures is definitely ingested, an individual or perhaps your son or daughter could possibly be asked in order to sip a liquid or perhaps get a intravenous (INTRAVENOUS) shot associated with a kind of dye of which allows far better outline areas inside system. The second pair of  Computed tomography (CT) check out pictures is definitely subsequently ingested. Lots of people are usually sensitized on the dye and find hives or perhaps a flushed sensation or perhaps, hardly ever, have got much more serious reactions like issues deep breathing and reduced continue pressure. Be sure you say to this physician in case you or perhaps your son or daughter provides ever had a response in order to any kind of vary fabric made use of to get x-rays.

Computed tomography (CT) reads require more time than usual x-rays. You might want to are situated continue to on the stand whilst they’re staying carried out. You may look rather enclosed by wedding ring you must are situated around should the pictures think you are ingested. Medical doctors might use medicinal drugs for a few children to hold these quiet or perhaps in bed during the test.

Occasionally, a Computed tomography (CT) is known to guide a biopsy filling device towards one place associated with matter. This is named a Computed tomography (CT)-guided filling device biopsy. An individual remain within the CT scanning stand whilst a radiologist proceeds a biopsy filling device through the pores and skin and towards this muscle size. A biopsy small sample is definitely subsequently taken out to get viewed inside science lab.

Over unity magnetic resonance imaging (MRI): The following test is definitely hardly ever used in Hodgkin disease, if you physician is worried regarding propagate on the spinal twine or perhaps head, MRI is very beneficial to get taking a look at all these areas. MRI reads utilize radio stations lake and powerful magnets rather than x-rays taking pictures. A product named gadolinium is sometimes shot in to a spider vein prior to check out in order to far better show facts. It doesn’t stop here normally lead to allergic reactions. MRI reads require more time than Computed tomography (CT) reads — often as long as an hour. You may have in order to are situated within a thin tube, which can angry of those with a anxiety associated with surrounded rooms. A few children might need medicines for making these quiet and sleepy.

Positron emission tomography (PET): PET reads require injecting a form of sugar that contains several radioactivity on the continue. The following sugar gathers inside cancer malignancy solar cells. Its own digicam are able to pick up this radioactivity and show this areas of cancer malignancy inside system. PET reads might help say to whether a enlarged lymph node is made up of Hodgkin disease. They’ve also been familiar with say to how properly medication is definitely working. Around taking a look at clients having Hodgkin disease, a equipment of which combines this PET check out that has a Computed tomography (CT) check out is sometimes made use of. All these reads might help pinpoint the complete location on the lymphoma much better than a CT on it’s own.

Gallium check out: In this test, a small measure associated with radioactive gallium is definitely shot in to a spider vein. The item goes toward lymph flesh inside system. A week subsequently its own digicam can be used to find the gallium. The following test discover tumors dress yourself in be Hodgkin disease around lymph nodes and also other internal organs. But isn’t made use of as often these days as before, for the reason that the majority of medical doctors accomplish a PET check out on the other hand.

Bone check out: A radioactive product is also made use of to get bone reads. After it can be shot, the item journeys in order to broken areas of this bone. Its own digicam are able to identify the item. Hodgkin disease sometimes creates bone deterioration, which may be picked up on the bone check out. The following test isn’t often carried out until somebody is definitely having bone pain or perhaps provides science lab test effects of which suggest this Hodgkin disease sometimes have climbed to this our bones.

The 2011-2016 World Outlook for Computed Tomography (CT) Scans and Magnetic Resonance Imaging (MRI) Tests

This econometric study covers the world outlook for computed tomography (CT) scans and magnetic resonance imaging (MRI) tests across more than 200 countries. For each year reported, estimates are given for the latent demand, or potential industry earnings (P.I.E.), for the country in question (in millions of U.S. dollars), the percent share the country is of the region and of the globe. These comparative benchmarks allow the reader to quickly gauge a country vis-a-vis others. Using econometric models which project fundamental economic dynamics within each country and across countries, latent demand estimates are created. This report does not discuss the specific players in the market serving the latent demand, nor specific details at the product level. The study also does not consider short-term cyclicalities that might affect realized sales. The study, therefore, is strategic in nature, taking an aggregate and long-run view, irrespective of the players or products involved.

This study does not report actual sales data (which are simply unavailable, in a comparable or consistent manner in virtually all of the 230 countries of the world). This study gives, however, my estimates for the worldwide latent demand, or the P.I.E. for computed tomography (CT) scans and magnetic resonance imaging (MRI) tests. It also shows how the P.I.E. is divided across the world’s regional and national markets. For each country, I also show my estimates of how the P.I.E. grows over time (positive or negative growth). In order to make these estimates, a multi-stage methodology was employed that is often taught in courses on international strategic planning at graduate schools of business.

The 2009-2014 Outlook for Computed Tomography (CT) Scans and Magnetic Resonance Imaging (MRI) Tests in Latin America

This econometric study covers the outlook for computed tomography (ct) scans and magnetic resonance imaging (mri) tests in Latin America. For each year reported, estimates are given for the latent demand, or potential industry earnings (P.I.E.), for the country in question (in millions of U.S. dollars), the percent share the country is of the region and of the globe. These comparative benchmarks allow the reader to quickly gauge a country vis-a-vis others. Using econometric models which project fundamental economic dynamics within each country and across countries, latent demand estimates are created. This report does not discuss the specific players in the market serving the latent demand, nor specific details at the product level. The study also does not consider short-term cyclicalities that might affect realized sales. The study, therefore, is strategic in nature, taking an aggregate and long-run view, irrespective of the players or products involved.

This study does not report actual sales data (which are simply unavailable, in a comparable or consistent manner in virtually all of the countries in Latin America). This study gives, however, my estimates for the latent demand, or the P.I.E. for computed tomography (ct) scans and magnetic resonance imaging (mri) tests in Latin America. It also shows how the P.I.E. is divided across the national markets of Latin America. For each country, I also show my estimates of how the P.I.E. grows over time (positive or negative growth). In order to make these estimates, a multi-stage methodology was employed that is often taught in courses on international strategic planning at graduate schools of business.

Recommended Reading

Be the first to comment - What do you think?
Posted by admin - 02/01/2012 at 5:23 pm

Categories: Lymphatic Cancer Treatment   Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Hodgkin’s Lymphoma and Brian’s Story: A Highly Curable Cancer

BRIAN’S STORY

Brian was a 20-year old college basketball star who was in excellent condition and had no history of health problems. He grew up in a tough neighborhood with a single mother who raised him to be a fine young gentleman. He was awarded a basketball scholarship to state college, where he became the league leading scorer during his junior year. When his mother came to visit for a game late in the season, she noticed that Brian’s neck appeared much larger on one side than the other. The next day, she convinced him to see the college physician who felt multiple enlarged lymph nodes in his right neck extending from the angle of the jaw down to just above his collarbone. The doctor ordered a CT scan of the neck and chest that confirmed multiple abnormal in the right side of the neck as well as the center of the chest. Brian was referred to a general surgeon who removed one of the larger in his neck during an outpatient surgery. This excisional biopsy revealed Hodgkin lymphoma.

Following his diagnosis, Brian was sent for a bone marrow biopsy which was negative. He also underwent a PET/CT scan that confirmed abnormal activity in the right neck and chest in multiple lymph nodes. Brian was referred to a medical oncologist who recommended treatment with ABVD chemotherapy. He received 4 cycles which he tolerated very well, with only moderate fatigue. A restaging PET/CT scan revealed no residual abnormal activity. He was seen by a radiation oncologist who recommended low dose involved field radiation therapy (IFRT) after chemotherapy which was delivered over 3 weeks. Other than a mild sore throat, Brian tolerated RT quite well. He was seen every 3-6 months by his medical and radiation oncologist for alternating follow-up visits. Brian has been free of disease for 7 years.

BASICS

Hodgkin’s lymphoma (HL) is much less common than non-Hodgkin lymphoma (NHL), though it may be in children as well as the elderly. If the disease is localized, then the 5-year survival is over 90%. Even patients with more advanced HL have a 5-year survival rate of 75-80%

RISKS & CAUSES

People who have history of a first degree relative diagnosed with Hodgkin’s Lymphoma are at a significantly increased risk of developing the disease themselves. In addition, patients who have Epstein-Barr virus (EBV) infection early in life appear to have an increased risk of Hodgkin’s Lymphoma later in life. There appears to be a correlation with patients of low socioeconomic status also.

SIGNS & SYMPTOMS

The vast majority of patients with Hodgkin’s Lymphoma will come to the doctor with the complaint of an enlarged lymph node or multiple lymph nodes that won’t go away. Most frequently the node will arise in the neck, but may also be felt in other common lymph node areas including the axilla (under the arm) and the groin. Doctors should also ask questions regarding unexplained weight loss, fevers, or drenching night sweats, the “B symptoms” that are classic for lymphoma. Although they are only present in a subset of patients, B symptoms tend to predict for more advanced disease. Rarely, patients may present with diffuse itching or flushing of the skin when drinking alcohol as an initial sign of HL.

DIAGNOSIS

Like Non Hodgkin’s Lymphoma, the preferred method of biopsy for Hodgkin’s Lymphoma is complete surgical removal of an enlarged lymph node (excisional biopsy) whenever feasible and safe. There are multiple subtypes of  Hodgkin’s Lymphoma including: nodular sclerosing, mixed cellularity, lymphocyte rich and lymphocyte depleted. Yet another subtype, called nodular lymphocyte predominant Hodgkin’s Lymphoma, appears to be biologically different from the others, but also has an extremely high cure rate.

STAGING

Standard laboratory evaluation should include complete blood count, serum chemistries including kidney and liver function, blood levels of lactate dehydrogenase (LDH) and erythrocyte sedimentation rate (ESR), the latter two of which have been shown to predict for more advanced disease when elevated. As with NHL, the Ann Arbor staging system is used. This system is based on the number and sites of involvement in lymph nodes and other organs, as well as the presence or absence of B symptoms. Imaging should include CT of involved areas including neck, chest, abdomen and pelvis. Wherever available, PET/CT is extremely useful for staging, radiation therapy (RT) planning, and assessing response to treatment. Bone marrow biopsies are indicated for patients with advanced disease including those who present with B symptoms. Other factors that may negatively impact outcome include male sex, age older than 45, low serum hemoglobin, high white blood cell count, low albumin, and stage IV disease.

TREATMENT

Like Non Hodgkin’s Lymphoma, Hodgkin’s Lymphoma is treated with a combination of chemotherapy drugs. In the case of Hodgkin’s Lymphoma, four drugs are utilized most commonly in the United States: adriamycin, bleomycin, vinblastine, and dacarbazine. The acronym for the combination is ABVD. Treatment of tens of thousands of patients over the past few decades with ABVD has shown consistently excellent results.

Patients with early stage HL generally receive 2-6 cycles of ABVD. Restaging imaging is obtained after 2-4 cycles to guide further treatment. PET restaging is predictive of outcome. The combination of ABVD followed by involved field radiation therapy (IFRT) yields an excellent chance for cure.

Common acute side effects of ABVD include fatigue, nausea (usually well-controlled with medication), mild anorexia, decreased blood counts, and hair loss. Uncommon but serious late side effects following treatment include heart damage from adriamycin, lung damage from bleomycin, and nerve damage from vinblastine. Chemotherapy does put patients at a slightly increased risk for development of future cancers, most commonly leukemia or NHL.

Since low doses and fairly small treatment areas are currently utilized for IFRT, side effects are much less than decades ago when the doses were higher and treatment areas were larger. Common acute side effects of IFRT include mild fatigue, possible partial alopecia (hair loss), and sore throat or difficulty swallowing, depending on the area treated. There is a risk of pneumonitis (inflammation of the lung) characterized by low-grade fever, dry cough, and shortness of breath with exertion, that occurs classically 1-3 months after RT. The 5-10% of patients who develop lung inflammation usually have resolution of their symptoms within 3-4 weeks after start of steroids. Long-term, despite the low doses and small RT fields, there remains a small risk of developing a radiation-induced cancer years after treatment. Patients should be encouraged to quit smoking prior to RT. Teenage girls and young women who require RT to the chest should begin annual mammogram (and usually breast MRI) screening within 7-10 years following treatment or at age 40, whichever comes first.

Advanced stage HL is treated most commonly with systemic chemotherapy alone, again predominantly ABVD in the U.S. Cure rates are about 70%. Patients may receive 6-8 cycles of ABVD, with restaging PET/CT performed after 4-6 cycles to assess response. The role of consolidative IFRT for these patients is controversial.

Dr. Maguire’s home reference book for the public, “When Cancer Hits Home,” has received excellent reviews from cancer survivors and experts alike:

When Cancer Hits Home
by: Patrick Maguire
publisher: Coastal Carolina Publishing LLC, published: 2011-01-30
ASIN: B004LLIWYU
sales rank: 258521

When Cancer Hits Home: Cancer Treatment and Prevention Options for Breast, Colon, Lung, Prostate, & Other Common Types by Patrick Maguire MD is a guidebook that everyone should have in their home. In the touching introduction, the author describes his family’s cancer journey. In Part I, Dr. Maguire provides valuable information on how to reduce the risk of getting cancer. He then tackles recent controversial topics including PSA testing and mammograms for early detection. In Part II, he discusses various treatment options for the 20 most common cancer types.

Written in plain English with minimal medical jargon, When Cancer Hits Home fills the gap between the many cancer survivor biographies and technical references in the marketplace today.
This highly readable guide is a single reliable source of cancer information for patients and their families.

Henry Kaplan and the Story of Hodgkin’s Disease
by: Charlotte Jacobs
publisher: Stanford General Books, published: 2010-04-01
ASIN: 0804768668
EAN: 9780804768665
sales rank: 431990
price: $19.75 (new), $11.90 (used)

In the 1950s, ninety-five percent of patients with Hodgkin’s disease, a cancer of lymph tissue which afflicts young adults, died. Today most are cured, due mainly to the efforts of Dr. Henry Kaplan. Henry Kaplan and the Story of Hodgkin’s Disease explores the life of this multifaceted, internationally known radiation oncologist, called a “saint” by some, a “malignant son of a bitch” by others. Kaplan’s passion to cure cancer dominated his life and helped him weather the controversy that marked each of his innovations, but it extracted a high price, leaving casualties along the way. Most never knew of his family struggles, his ill-fated love affair with Stanford University, or the humanitarian efforts that imperiled him.

Today, Kaplan ranks as one of the foremost physician-scientists in the history of cancer medicine. In this book Charlotte Jacobs gives us the first account of a remarkable man who changed the face of cancer therapy and the history of a once fatal, now curable, cancer. She presents a dual drama —the biography of this renowned man who called cancer his “Moby Dick” and the history of Hodgkin’s disease, the malignancy he set out to annihilate. The book recounts the history of Hodgkin’s disease, first described in 1832: the key figures, the serendipitous discoveries of radiation and chemotherapy, the improving cure rates, the unanticipated toxicities. The lives of individual patients, bold enough to undergo experimental therapies, lend poignancy to the successes and failures.

Non Hodgkins Lymphomas: New Techniques and Treatments
by: J.J. Sotto
publisher: S Karger Pub, published: 1985-06
ASIN: 3805540647
EAN: 9783805540643
sales rank: 10317378
price: $191.00 (new), $85.36 (used)

To learn more or read Dr. Maguire’s blog, visit: http://patrickmaguiremd.com/

Recommended Reading

1 comment - What do you think?
Posted by admin - 28/12/2011 at 5:24 pm

Categories: Lymphatic Cancer   Tags: , , , , , , , , ,

How to Treat Canine Lymphoma

Canine lymphoma is a malignant that frequently strikes dogs of middle age. Any breed can contract it, but it seems that Golden Retrievers tend to develop it more than others. If you’re the owner of a middle aged dog, particularly a Golden Retriever, you may be interested in knowing what the treatment options are should your dog develop this type of cancer.


Chemotherapy is highly effective in treating canine lymphoma. Most effective are multi-agent chemotherapy regimens that employ a combination of drugs. There has been more success with this regimen than with treatment using only a single drug.


Eighty percent of dogs that receive multi-agent chemotherapy regimens go into a year-long remission. While it’s possible for them to experience a second remission, it’s typically not as long as the first one. As some of the cancer cells will develop a resistance to the first round of drugs used, there will be a need to find the right regimen of drugs for the second remission to work. This is done by simple trial and error. It should be noted that even though the multi-agent regimen increases the dog‘s life span, they are more expensive and toxic than single drug regimens.


How successful the chemotherapy treatment is depends on where the tumor is located, what stage the cancer is in, and how healthy the dog is when the cancer is diagnosed. Lymphoma of the bone marrow or the thymus decrease chances for a remission. Dogs that aren’t exhibiting any signs such as diarrhea and vomiting and seem to feel well at the initial diagnosis seem to respond better to chemotherapy. Side effects of chemotherapy in dogs are usually minimal and mild. These may include loss of appetite, diarrhea, vomiting and low blood cell count.


Prednisone, a type of corticosteroid, can provide up to 2 to 3 months remission. This method is used when the dog isn’t a good candidate for chemotherapy or the owner can’t afford the expense of it. This basically makes the dog‘s remaining time more comfortable.


While one university offers canine bone marrow transplant, this is a highly expensive procedure. It offers a 30 percent cure rate so far. They’re hoping to make that higher in the future.


Summary
Canine lymphoma seems to typically affect middle aged dogs but is not as hopeless as it used to be when you choose the proper treatment.


Want to learn more about dog lymphoma? On CanineLymphoma.Net you can find articles about dog lymphoma dealing with the main symptoms of dog lymphoma, treatment of dog lymphoma and about the effects of chemotherapy on dogs.

Recommended Reading

Be the first to comment - What do you think?
Posted by admin - 10/12/2011 at 5:19 am

Categories: Lymphatic Cancer In Dogs   Tags: , , , , , , , , ,

Malignant Lymphoma : Treatment, Diagnosis And Prevention

Malignant are a group of cancers in which cells of the lymphatic system become abnormal and start to grow uncontrollably. Because there is lymph tissue in many parts of the body, lymphomas can start in almost any organ of the body.

The of malignant lymphoma requires the presence of malignant lymphocytes in a biopsy of or extra-lymphatic tissue. An excisional biopsy is essential for complete diagnostic assessment. If a whole is not obtainable, sufficient incised tissue from an extra-lymphatic site can be diagnostic but is less desirable. Fine needle aspiration biopsy (see Appendix I: Biopsy Procedures) is not sufficient for the initial diagnosis of malignant lymphoma.

The following histologic sub-classification of the malignant lymphomas is an adaptation of the Working Formulation and the WHO/REAL classification (Jaffe E, Tumours of Hematopoietic and Lymphoid Tissues, World Health Organization Classification of Tumours, IARC Press, 2001) and is based on the light microscopic interpretation complemented by special stains, immunophenotyping, cytogenetics and other information as available. The specific lymphomas are divided into three major groups for treatment planning.

Treatment of malignant lymphoma.

Malignant lymphomas are increasing in frequency for unknown reasons. We know today that they constitute a big family of tumours of lymphoproliferative origin, which can be very different one from the other in terms of morphology, biology, and clinical behaviour. Some of them need very specific treatments and it is therefore important that a clear diagnosis is obtained and that the treatment is administered by specialised doctors. Although the new WHO classification has abolished the concepts of low-grade and high-grade lymphomas, it remains true that some lymphatic cancers exhibit indolent behaviour and cannot be cured, while other aggressive lymphomas can be cured by modern therapy. The cornerstone of treatment remains chemotherapy and, to a minor extent, radiotherapy. New treatment modalities such as the use of monoclonal antibodies, high-dose therapy or allogenic transplantation have improved the treatment results in the last decade. In this article we offer a summary of the most important concepts which are of interest for practising physicians.

Diagnosis of malignant lymphoma

An immunoperoxidase method for distinguishing lymphomas from nonlymphoid neoplasms with monoclonal antibody T29/33 is described. This antibody recognizes a 200,000-dalton pan-hematopoietic glycoprotein antigen. Staining in nearly 200 hematopoietic tumors was positive for T29/33, although three of six plasmacytomas were negative for this antibody. Five undifferentiated tumors that were proved to be lymphomas by subsequent electron microscopic and immunohistologic studies were positive for T29/33. Conversely, 11 of 12 undifferentiated tumors with ultrastructural and clinical features of carcinoma or sarcoma were T29/33-negative. The only exception was one sarcoma that was T29/33-positive. Thus, monoclonal antibody T29/33 is a valuable tool for characterizing neoplasms that cannot be diagnosed by histopathologic examination alone.

Malignant lymphoma prevention

Preventive measures, when initiated early, may help patients with NHL/CLL who have a higher risk of developing NMSC in the future. Patients who have significantly sun-damaged skin with multiple actinic keratoses may be candidates for aggressive regional treatments with either topical chemotherapy or photodynamic therapy. Aggressive treatment of these chronically sun-damaged sites may prove beneficial in decreasing the development and aggressive behavior of NMSC in these patients. Effective sun-protective efforts in patients with NHL/CLL is also important.

A patient with NHL/CLL that sun protects rigorously on a daily basis may be at risk for vitamin D deficiency. Patients with NHL/CLL and a history of multiple aggressive and/or recurrent NMSC may be considered for systemic retinoids and perhaps other forms of preventive systemic chemotherapy.

Female and male infants have essentially the same overall cancer incidence rates, but white infants have substantially higher cancer rates than black infants for most cancer types. Relative survival for infants is very good for neuroblastoma, Wilms’ tumor and retinoblastoma, and fairly good (80%) for leukemia, but not for most other .

Tips on Cancer Prevention

1. Limit alcohol.

2. Maintain a healthy weight.

3. Stay physically active.

4. Consider limiting fat in your diet.

5. Avoid prolonged exposure to the sun and other UVA/UVB sources, such as tanning beds.

6. Use ample amounts of sunscreen or sunblock with an SPF of 15 or higher every day, even if it is cloudy.

7. Wear large framed or wrap-around sunglasses to protect the eye area.

8. Have your skin checked by a dermatologist regularly.

9. Do avoid all poisonous chemical substances such as cigarettes, alcohol, car exhaust fumes, as well as fumes belched by factory chimneys, which are very toxic.

10. Anilin is a carcenogenic substance used for colouring food, so try to avoid artificially dyed foods and instead look for natural foods.

Reference of malignant lymphoma

Malignant Lymphomas: Biology and Treatment: An Update (ESO Monographs)

In the last few years a good deal of information related to the biology and treatment of malignant lymphomas has been accumulated and published in journals and monographs. There is, however, no book that gives a concise and objective update of this information or presents a general survey of the subject. The contributors to this book are international authorities, and on the basis of their personal experience and data from the literature they have written a high-level update on malignant lymphomas which will be of interest to both specialists and nonspecialists.

Malignant Lymphomas (Atlas of Clinical Oncology.)

Malignant Lymphomas is a volume in the acclaimed American Cancer Society Atlas of Clinical Oncology series. Dr. Grossbard and his team have summarized current knowledge on the pathology, epidemiology, molecular biology, presentation and management of patients with both non-Hodgkin’s lymphoma and Hodgkin’s disease. The experts address the disease group by type – indolent B-cell lymphoma, diffuse large cell lymphomas, Burkitt’s/high-grade non-Hodgkin’s lymphoma – as well as the key therapies of chemotherapy, monoclonal antibody, radiation, vaccine, hematopoietic stem cell transplants and more. This text’s multi-author approach is a necessity now that management and classification of lymphoma have grown so complex. Malignant Lymphomas will be a valuable resource in the practice of those seeing patients with the disease, as well as a springboard for the continued inquiry into advances being made into the pathophysiology, diagnosis and management of lymphoma.

Malignant Lymphoma

This text discusses the full range of scientific and clinical developments that have occurred in the investigation and treatment of Hodgkin’s disease and non-Hodgkin’s lymphomas. With contributions from around the world, it covers both current views and likely future developments, and addresses a broad spectrum of clinical care, from the routine to the highly experimental.

[table id=4 /]

Recommended Reading

1 comment - What do you think?
Posted by admin - 15/11/2011 at 9:12 am

Categories:   Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Lymphoma in Dogs – Pros and Cons of Lymphoma Treatment

Dog lymphoma is a cancer of lymphocytes or white blood cells. It is a common type cancer that affects the lymphatic system in dogs.


Lymphoma symptoms in dogs


The specific symptoms are determined by the type of lymphoma in dogs. The most common type develops as lumps or swollen lymph glands on the neck, legs and shoulders. There is no pain or discomfort in the early stages. The enlarged lymph nodes are usually discovered by accident.


Other less common types of dog lymphoma affect the digestive tract, thymus glands or skin. The symptoms include vomiting, diarrhea, tiredness, breathing difficulty, lesions on skin and loss of appetite.


In the advanced stages of lymphoma, the general symptoms include weight loss, anemia, loss of appetite and weakness. As the lymph circulates throughout the body, other organs such as the spleen, liver and bone marrow can be affected. If left untreated, dogs with lymphoma have a life expectancy of 4-6 weeks following diagnosis.


Dog lymphoma treatment


Lymphoma in dogs can be treated with chemotherapy, prednisone therapy and blood stem cell transplant.


Chemotherapy


Chemotherapy is the main treatment for lymphoma in dogs. With this treatment, more than 80% of dogs will go into remission for at least 12 months. The numerous chemotherapy protocols are either multi-agent or single-agent.


Multi-agent chemotherapy involves a combination of drugs given orally or by injections. It is more effective than single-agent chemotherapy and produces longer remission. However, toxicity and the risk of unwanted side effects are higher as more drugs are used. This type of chemotherapy requires greater time commitment and bigger expense.


Single-agent chemotherapy protocol uses one chemotherapy drug. It is less toxic and costly than multi-agent chemotherapy. Any adverse side effect is attributed to the single drug, so a different drug can be used instead. As it is less effective than multi-agent chemotherapy, the first remission period is shorter, about 7 months.


The duration of remission and choice of chemotherapy protocols depend on the primary location of tumor, lymphoma stage, overall health of dog at the beginning of treatment and any changes in organ function. Most dogs respond to chemotherapy with minimal (if any) side effects. The common side effects are nausea, loss of appetite, diarrhea, vomiting, tiredness, hair loss and slow hair growth. Serious side effects are rare and only seen in 5-10% of dogs.


Prednisone therapy


Lymphoma in dogs can be treated with prednisone (corticosteroid) where chemotherapy is not recommended. Chemotherapy can be costly, so some pet owners choose prednisone therapy instead. Dogs given prednisone experience significant improvement in the short term and can lead a more comfortable life. Although sick, they eat, move and feel better while undergoing prednisone therapy.


Although prednisone therapy is inexpensive, it is not as effective as chemotherapy. Remission is short, about 2-3 months with possible side effects. Prednisone therapy should not be carried out prior to chemotherapy as it reduces the effectiveness of the latter.


Blood stem cell transplant


Stem cells are harvested from bone marrow. Only stem cells that are free from cancer are reintroduced into the dog after it has undergone total body radiation to kill of remaining cancer cells in the body.


Although this treatment raises the survival rate significantly, it is very expensive.


Your vet can advise you on the most suitable lymphoma treatment for your dog. You want to consider the costs, time commitment, life span and your dog’s comfort in deciding whether to proceed with treatment.

Recommended Reading

3 comments - What do you think?
Posted by admin - 12/11/2011 at 8:57 am

Categories: Lymphatic Cancer In Dogs   Tags: , , , , , , , , ,

Lymphatic Cancer ( Lymphoma )

Lymphatic cancer ( Lymphoma ) is a cancer in the lymphatic cells of the immune system. Typically, present as a solid tumor of lymphoid cells.

Thomas Hodgkin published the first description of Lymphatic cancer (lymphoma) in 1832, specifically of the form named after him, Hodgkin’s lymphoma. It introduced the (NHL), divided into 16 different diseases. The latest classification by the WHO (2008) lists 70 different forms of lymphoma divided in four broad groups.

Although older classifications referred to histiocytic lymphomas, Lymphatic cancer are recognized in newer classifications as of B, T or NK cell lineage.

A number of various different classification systems exist for lymphoma. Some forms of Lymphatic cancer are categorized as indolent (e.g. small lymphocytic lymphoma), compatible with a long life even without treatment, whereas other forms are aggressive (e.g. Burkitt’s lymphoma), causing rapid deterioration and death.

Hodgkin’s Lymphoma or Lymphatic cancer (formerly Hodgkin’s disease)

Named after the Doctor, Thomas Hodgkin, who first identified the disease in 1832, Hodgkin’s lymphoma ( Lymphatic cancer )is one of the most common cancers among younger people, although still relatively rare. It affects young adults aged between 15 and 35, and adults over the age of 55. More men than women are affected. The disease, although aggressive, can be successfully treated in about 80 per cent of cases.

It is defined by the presence of a large, abnormal B-lymphocyte cell. (This is called a Reed-Sternberg cell.) B-lymphocytes are produced in the body in response to invasion by a foreign body. This could typically be a virus or bacterium, but could include a toxin or a chemical.

Organs that have lymphoid tissue

Because lymphoid tissue is in many parts of the body, lymphatic cancer can start almost anywhere. The major sites of lymphoid tissue are:

Lymph nodes: Lymph nodes are bean-sized organs throughout the body that are connected by a system of lymphatic vessels. These vessels are like veins, except that instead of carrying blood, they carry lymph and immune system cells.

Lymph nodes get bigger when they fight infection. Lymph nodes that grow in reaction to infection are called reactive nodes or hyperplastic nodes and are often tender to the touch. An enlarged is not always a sign of a serious problem. People with sore throats or colds often feel enlarged lymph nodes in the neck. But a large is also the most common sign of lymphoma. enlargement is discussed more in the section, ”

How is non-Hodgkin lymphoma diagnosed?

Spleen: The spleen is an organ under the lower part of the rib cage on the left side of the body. An average adult spleen weighs about 5 ounces. The spleen makes lymphocytes and other immune system cells to help fight infection. It also stores healthy blood cells and filters out damaged blood cells, bacteria, and cell waste.

Thymus gland: The thymus lies behind the upper part of the breastbone and in front of the heart. Before birth, the thymus plays a vital role in development of T lymphocytes. The thymus shrinks and becomes less important over the first 20 years of life. Despite this, it continues to play a role in immune system function.

Adenoids and tonsils: These are collections of lymphoid tissue at the back of the throat. They help make antibodies against germs that are breathed in or swallowed. They are easy to see when they become enlarged during an infection or if they become cancerous.

Digestive tract: The stomach and intestines as well as many other organs also have lymphoid tissue.

Bone marrow: The bone marrow (the soft inner part of certain bones) makes red blood cells, blood platelets, and white blood cells. Red blood cells carry oxygen from the lungs to the rest of the body. Platelets plug up small holes in blood vessels caused by cuts or scrapes. White blood cells’ main job is fighting infections. The 2 main types of white blood cells are granulocytes and lymphocytes. Bone marrow lymphocytes are primarily B cells. Lymphatic cancer sometimes start from bone marrow lymphocytes.

There are 5 different types of Hodgkin’s lymphoma or Lymphatic cancer.   These 5  types are based on the way they look under a microscope.

  1. Nodular sclerosing Hodgkin’s lymphoma.
  2. Mixed cellularity Hodgkin’s lymphoma.
  3. Lymphocyte depletion Hodgkin’s lymphoma.
  4. Lymphocyte-rich classical Hodgkin’s lymphoma.
  5. Nodular lymphocyte-predominant Hodgkin’s lymphoma.

 

The Lymphatic System and Cancer: Mechanisms and Clinical Management (Frontiers of Radiation Therapy and Oncology) (v. 28)

We are entering a new era of understanding the lymphatic system based on important insights from experimental investigations and clinical trials. To achieve a cure, cancer therapies (whether by surgery, radiotherapy or systemic means) must be directed against the routes of cancer spread. The management of the regional lymphatic/lymph nodes, often the first site of involvement, is frequently a key decision in defining modern treatment programmes. Important new insights now challenge the basis of traditional cancer therapy recommendations. This volume brings together foremost authorities to outline the latest results in the management of the lymphatic system in cancer.

Clinical Lymphatic Mapping of Gynecologic Cancer

The first comprehensive text of lymphatic mapping in gynecological cancers, Clinical Lymphatic Mapping of Gynecologic Cancer, provides a historical perspective, an understanding of the associated modalities of pathology and diagnostic imaging, a disease site-specific review of the literature, and step-by-step descriptions of how to identify sentinel nodes. The text is fully illustrated, allowing readers to grasp the techniques as well as the analysis of the results. The editors address the entire breadth of the topic, making this an ideal reference source for newly qualified professionals and students in gynecological oncology

Lymphatic Cleansing (Helping Hands, 2)

Whether your body is battling cancer, or any number of diseases or disorders, manual stimulation of the lymph system will help you maintain a greater degree of health. The lymphatic system, designed to cleanse and detoxify body cells, is perhaps your greatest ally during the treatment phase surrounding cancer. However, when lymphatic tissue or lymph nodes have been damaged, destroyed or removed, normal lymph drainage is compromised. Through this nurturing Lymphatic Cleasing meditation, enhanced with soothing melodies and calming rhythms, you will learn to reactivate sluggish lymph glands, as your body creates new pathways for channeling and purifying the body’s waste products.

Recommended Reading

11 comments - What do you think?
Posted by admin - 23/10/2011 at 12:45 pm

Categories:   Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

You might also likeclose
This site is protected by WP-CopyRightPro